Single-molecule long-read sequencing reveals the chromatin basis of gene expression
Yunhao Wang, Anqi Wang, Zujun Liu, Andrew L. Thurman, Linda S. Powers, Meng Zou, Yue Zhao, Adam Hefel, Yunyi Li, Joseph Zabner, Kin Fai Au
The paper introduces MeSMLR-seq to study chromatin accessibility and nucleosome organization at the single-cell level in yeast, revealing correlations between chromatin states and gene transcription.
Genome Research · Aug 1, 2019Peer-reviewedBioinformatics