Engineered probiotics target granulomas to treat mycobacterial infection
Yu-Yu Chen, Tetsuhiro Harimoto, Gaëlle Guiewi Makafe, Courtney Coker, Hannah Kim, Jongwon Im, Yuanqi Jing, 진하영, Xiaoyu Hu, Sharicka Zutshi, Mia Ross Raneri, Brian C. Weinrick, Tal Danino
This paper engineers probiotic bacteria to target granulomas and reduce mycobacterial infection in vitro and in vivo.
bioRxiv · Oct 29, 2026 · PreprintSynthetic Biology