Author

Michael Cashel

National Institutes of Health

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Elena V. SinevaiD· 1 shared Katsuhiko S. MurakamiiD· 1 shared Lu ZhangiD· 1 shared Sarah E. AdesiD· 1 shared Vadim MolodtsoviD· 1 shared Xuhui HuangiD· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperMolecular Biology

Elena V. SinevaORCID

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1 paper

Recent·Most cited

Allosteric effector ppGpp potentiates the inhibition of transcript initiation by DksA

Vadim Molodtsov, Elena V. Sineva, Lu Zhang, Xuhui Huang, Michael Cashel, Sarah E. Ades, Katsuhiko S. Murakami

This study reports the X-ray crystal structures of E. coli RNA polymerase complexes with DksA and ppGpp, revealing how ppGpp enhances DksA's inhibition of transcription initiation.

Molecular Cell · Feb 22, 2018Peer-reviewedMolecular Biology