Evolutionarily Conserved Roles For Blood-Brain Barrier Xenobiotic Transporters In Endogenous Steroid Partitioning And Behavior
Samantha J. Hindle, Roeben N. Munji, Elena Dolghih, Garrett Gaskins, Souvinh Orng, Hiroshi Ishimoto, Allison Soung, Michael K. DeSalvo, Toshihiro Kitamoto, Michael J. Keiser, Matthew P. Jacobson, Richard Daneman, Roland J. Bainton
The paper shows BBB efflux transporters regulate endogenous steroids and behaviors, and drug interactions with these transporters cause behavioral side effects.
Cell Reports · Oct 1, 2017Peer-reviewedNeuroscience