Inhibition of serine and arginine-rich splicing factor 3 induces epidermal differentiation and decreases cutaneous squamous cell carcinoma risk
Isoline M. Donohue, Haiyin He, Audrey D. Nguyen, Gavin Hui, Jananee Muralidharan, W. T. Pike, Michael L. Jackson, Christine J. Ko, Ankit Srivastava, Carolyn S. Lee
This study shows that inhibiting SRSF3 promotes epidermal differentiation and reduces cSCC risk, supported by clinical data on existing inhibitors.
bioRxiv · Nov 7, 2024 · PreprintCancer Biology