Author

Carolyn S. Lee

Stanford UniversityORCID 0000-0002-6511-3757Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ankit SrivastavaiD· 2 shared Audrey D. NguyeniD· 2 shared Isoline M. DonohueiD· 2 shared Aiko J. Tan· 1 shared Angela MahiD· 1 shared Chaw‐Ning LeeiD· 1 shared Christine J. KoiD· 1 shared Christopher M. RoseiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Ankit SrivastavaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Epithelial tumor cells utilize mast cell-derived histamine to regulate perineural invasion

Ankit Srivastava, Tomas Bencomo, Chaw‐Ning Lee, Angela Mah, Jasmine M. Garcia, Lek Wei Seow, Isoline M. Donohue, Aiko J. Tan, Audrey D. Nguyen, Tiffany Jiang, Saurabh Gombar, Lilian Phu, Pankaj Dwivedi, Christopher M. Rose, Ryanne A. Brown, Carolyn S. Lee

This study identifies mast cell-derived histamine as a regulator of perineural invasion in epithelial cancers, showing that H1-antihistamines improve survival and immunotherapy response.

bioRxiv · Jun 23, 2025 · PreprintCancer Biology

Inhibition of serine and arginine-rich splicing factor 3 induces epidermal differentiation and decreases cutaneous squamous cell carcinoma risk

Isoline M. Donohue, Haiyin He, Audrey D. Nguyen, Gavin Hui, Jananee Muralidharan, W. T. Pike, Michael L. Jackson, Christine J. Ko, Ankit Srivastava, Carolyn S. Lee

This study shows that inhibiting SRSF3 promotes epidermal differentiation and reduces cSCC risk, supported by clinical data on existing inhibitors.

bioRxiv · Nov 7, 2024 · PreprintCancer Biology