Author

Michael Lucas

University of Michigan

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aditya V. Suryakumar· 1 shared Allison G. Snyder· 1 shared Clare M. WielandiD· 1 shared Corey Stewart· 1 shared Elizabeth M.H. TankiD· 1 shared Emile S. PinarbasiiD· 1 shared Jacob Waksmacki· 1 shared Jen Bai· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aditya V. Suryakumar

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1 paper

Recent·Most cited

TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms

Megan M. Dykstra, Kaitlin Weskamp, Nicolás Gómez, Jacob Waksmacki, Elizabeth M.H. Tank, M. Rebecca Glineburg, Allison G. Snyder, Emile S. Pinarbasi, Michael E. Bekier, Xingli Li, Jen Bai, Shameena Shahzad, Juno Nedumaran, Clare M. Wieland, Corey Stewart, , Sami J. Barmada

This study identifies TDP43 autoregulation as a source of shortened isoforms, showing they are regulated by NMD and post-translational degradation, and their dysregulation leads to neurodegeneration.

bioRxiv · Jul 2, 2024 · PreprintNeuroscience