Author

Kaitlin Weskamp

Nebraska Wesleyan UniversityORCID 0000-0003-4474-2850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1

Frequent Co-Authors

Elizabeth M.H. TankiD· 2 shared Jonathon P. McBrideiD· 2 shared Nicolás GómeziD· 2 shared Sami J. BarmadaiD· 2 shared Aditya V. Suryakumar· 1 shared Allison G. Snyder· 1 shared Andrea SerioiD· 1 shared Carmen Moreno-GonzaleziD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Elizabeth M.H. TankORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 2, 2024

TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms

Megan M. Dykstra, Kaitlin Weskamp, Nicolás Gómez…·Sami J. Barmada

This study identifies TDP43 autoregulation as a source of shortened isoforms, showing they are regulated by NMD and post-translational degradation, and their dysregulation leads to neurodegeneration.

1 citation

humanexperimental assay

𝕏 PostBluesky

NeuroscienceJournal of Clinical InvestigationPeer-reviewedNov 12, 2019

Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS

Kaitlin Weskamp, Elizabeth M.H. Tank, Roberto Miguez…·Sami J. Barmada

This study shows that shortened TDP43 isoforms, upregulated by neuronal hyperactivity, drive TDP43 pathology in ALS by forming cytoplasmic inclusions and sequestering full-length TDP43.

126 citationstop 1%

𝕏 PostBluesky