Integrative Epigenomic Landscape of Alzheimer's Disease Brains Reveals Oligodendrocyte Molecular Perturbations Associated with Tau
Stephanie R. Oatman, Joseph S. Reddy, Amin Atashgaran, X. Wang, Yuhao Min, Zachary Quicksall, Floor Vanelderen, Minerva M. Carrasquillo, Chia‐Chen Liu, Yu Yamazaki, Thuy T. Nguyen, Michael M. Heckman, Na Zhao, Michael A. Deture, Melissa Erin Murray, , Nilüfer Ertekin‐Taner
The paper identifies epigenetic changes in Alzheimer's disease brains linked to tau pathology, highlighting oligodendrocyte gene perturbations as a potential common mechanism across tauopathies.
Nature Communications · Mar 3, 2026Peer-reviewedGenomics