Author

Yu Yamazaki

Mayo ClinicORCID 0000-0002-0806-4960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Takahisa KanekiyoiD· 3 shared Chia‐Chen LiuiD· 2 shared Dennis W. DicksoniD· 2 shared Guojun BuiD· 2 shared Joseph S. ReddyiD· 2 shared Mariet AlleniD· 2 shared Melissa Erin MurrayiD· 2 shared Michael A. DetureiD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Takahisa KanekiyoORCID

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3 papers

Recent·Most cited

Integrative Epigenomic Landscape of Alzheimer's Disease Brains Reveals Oligodendrocyte Molecular Perturbations Associated with Tau

Stephanie R. Oatman, Joseph S. Reddy, Amin Atashgaran, X. Wang, Yuhao Min, Zachary Quicksall, Floor Vanelderen, Minerva M. Carrasquillo, Chia‐Chen Liu, Yu Yamazaki, Thuy T. Nguyen, Michael M. Heckman, Na Zhao, Michael A. Deture, Melissa Erin Murray, , Nilüfer Ertekin‐Taner

The paper identifies epigenetic changes in Alzheimer's disease brains linked to tau pathology, highlighting oligodendrocyte gene perturbations as a potential common mechanism across tauopathies.

Nature Communications · Mar 3, 2026Peer-reviewedGenomics

Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's Disease related proteins

Stephanie R. Oatman, Joseph S. Reddy, Zachary Quicksall, Minerva M. Carrasquillo, Xue Wang, Chia‐Chen Liu, Yu Yamazaki, Thuy Nguyen, Kimberly G. Malphrus, Michael G. Heckman, Kristi Biswas, Kwangsik T. Nho, Matthew Baker, Yuka A. Martens, Na Zhao, , Nilüfer Ertekin‐Taner

This study performs a genome-wide association study of brain biochemical phenotypes in Alzheimer's patients, identifying novel genetic loci and highlighting distinct genetic architectures for AD-related proteins.

Molecular Neurodegeneration · Jan 6, 2023Peer-reviewedGenetics

Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimers mouse model

Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace A. Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal K. Dehankar, Cory C. Funk, Jordan Maximillian Wilkins, Анна Степанова, , Eugenia V. Trushina

The paper shows that partial inhibition of mitochondrial complex I protects against neurodegeneration in Alzheimer's mice by improving energy homeostasis, synaptic function, and reducing inflammation.

Communications Biology · Jan 8, 2021Peer-reviewedNeuroscience