Author

Michael O. Dorschner

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Wendy H. RaskindiD· 2 shared Alexander V. RatushnyiD· 1 shared Anna Maria EleuteriiD· 1 shared Annarita AttiliiD· 1 shared C. Anthony BlauiD· 1 shared Cathy L. BarriD· 1 shared Chao-Zhong Song· 1 shared Choli LeeiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersGenetics

Wendy H. RaskindORCID

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Author profile →

4 papers

Recent·Most cited

Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts

Nicola H. Chapman, Patrick A. Navas, Michael O. Dorschner, Michele G. Mehaffey, Karen G. Wigg, Kaitlyn M. Price, Oxana Yu. Naumova, Elizabeth Nellis Kerr, Sharon Guger, Maureen W. Lovett, Elena L. Grigorenko, Virginia Wise Berninger, Cathy L. Barr, Ellen M. Wijsman, Wendy H. Raskind

This study analyzes non-coding variants in five dyslexia candidate genes using targeted sequencing in large families, finding significant associations with reading and spelling traits but no large-effect coding variants.

PLoS ONE · May 27, 2025Peer-reviewedGenetics

Homozygous CADPS2 mutations cause neurodegenerative disease with Lewy bodies in parrots

Oswaldo Lorenzo‐Betancor, Livio Galosi, Laura Bonfili, Anna Maria Eleuteri, Valentina Cecarini, Ranieri Verin, Fabrizio Dini, Annarita Attili, Sara Berardi, Lucia Biagini, Patrizia Robino, Maria Cristina Stella, Dora Yearout, Michael O. Dorschner, Debby W. Tsuang, , Cyrus P. Zabetian

This study identifies a homozygous CADPS2 mutation in parrots causing neurodegenerative disease with Lewy bodies and reduced proteasome activity.

bioRxiv · Mar 30, 2022 · PreprintNeuroscience

TREM2 R47H exacerbates immune response in Alzheimer's disease brain

Olena Korvatska, Kostantin Kiianitsa, Alexander V. Ratushny, Mark M. Matsushita, Neal E. Beeman, Wei‐Ming Chien, J. Satoh, Michael O. Dorschner, Christopher Dirk Keene, Theo K. Bammler, Thomas D. Bird, Wendy H. Raskind

This study investigates how the TREM2 R47H variant affects immune responses in Alzheimer's disease by comparing gene expression in different patient groups.

bioRxiv · Aug 4, 2020 · PreprintGenetics

Comprehensive statistical inference of the clonal structure of cancer from multiple biopsies

Jie Liu, John T. Halloran, Jeffrey A. Bilmes, Riza M. Daza, Choli Lee, Elisabeth M. Mahen, Donna E. Prunkard, Chao-Zhong Song, Sibel H. Blau, Michael O. Dorschner, Vijayakrishna K. Gadi, Jay Shendure, C. Anthony Blau, William Stafford Noble

This paper introduces THEMIS, a method for analyzing tumor heterogeneity across multiple biopsies, showing improved accuracy over existing methods and applications in tracking cancer progression and treatment resistance.

Scientific Reports · Nov 29, 2017Peer-reviewedBioinformatics