Theo K. Bammler

This study identifies microRNA signatures associated with spontaneous preterm birth and links them to target genes involved in immune signaling and oxidative phosphorylation.

This study investigates the molecular effects of prenatal cannabis exposure on human fetal brains, finding significant disruptions in male second trimester brains linked to neurodevelopmental disorders.

This study compares voclosporin and cyclosporine A in 3D kidney MPS, finding that voclosporin preserves mitochondrial function and reduces proteostatic stress compared to cyclosporine A.

The paper investigates how sex chromosome aneuploidy affects gene expression and DNA methylation in different cell types, revealing cell-type specific dosage compensation mechanisms.

EpiBrain visualizes whole-brain epigenetic changes in zebrafish following perturbations like brain activity and chemical exposure, revealing gadd45b's role in experience-induced epigenetic modifications.

This study compares the transcriptomic profiles of LPS-induced immune responses in homeRNA and venous blood samples, showing homeRNA captures comparable inflammatory responses.

This study identifies placental transcriptome genes and modules mediating the effect of prenatal phthalate exposure on placental efficiency and fetal growth.

The paper shows that butyrate rescues CPF-induced social deficits in zebrafish by inhibiting class I HDACs, linking CPF exposure to gut microbiome, metabolome, and epigenetic changes.

This study investigates OTA toxicity in human kidney cells, showing it causes mitochondrial dysfunction, oxidative stress, and reduced energy production, contributing to kidney disease.

This study shows that mitochondrial calcium signaling regulates branched-chain amino acid catabolism and the urea cycle in fibrolamellar carcinoma through transcriptional control of metabolic genes.

This study evaluates RNA degradation in homeRNA-stabilized blood under varying shipping times and temperatures, finding that samples remain suitable for RNA sequencing under typical shipping conditions.

This study identifies macrophage activation as a key mechanism by which GBA mutations contribute to neuropathology in a Drosophila model.

This study evaluates the rigor and reproducibility of digital spatial profiling in clinically sourced human tissues, finding it to be highly reliable.

This study examines the association between prenatal vitamin D levels and placental gene expression, finding 25 differentially expressed genes linked to mid-pregnancy vitamin D levels.

The paper constructs a genome-scale transcriptional regulatory network of the human placenta using genomic and transcriptomic data, identifying key regulators of preterm birth.

The paper presents an improved chromosome-scale genome assembly for the African spiny mouse using long Nanopore reads and validates it with RNA-seq data.

The paper creates ancestry-specific linkage disequilibrium block maps for GRCh38, providing updated LD blocks for four populations.

The paper analyzes lifespan variation in wild yeast isolates to identify genetic and environmental factors shaping replicative lifespan and cellular processes involved in aging.

This study investigates how the TREM2 R47H variant affects immune responses in Alzheimer's disease by comparing gene expression in different patient groups.