Ellen M. Wijsman

This paper proposes a method to correct for multiple testing in IBD mapping for case-control studies, identifies six genome-wide significant AD risk loci, and shows positive selection can confound results.

This study analyzes non-coding variants in five dyslexia candidate genes using targeted sequencing in large families, finding significant associations with reading and spelling traits but no large-effect coding variants.

This study identifies genetic loci and candidate genes associated with essential hypertension in African-Brazilian Quilombo populations using genome-wide linkage analysis and family-based association studies.

The paper investigates the association of common and rare variants with Alzheimer's Disease in 13,371 diverse individuals using whole-genome sequencing, identifying significant genetic loci and population-specific associations.

This study uses whole genome sequence data from the ADSP to identify 17 significant variants in five genomic regions associated with Alzheimer's disease.

GIGI2 improves genotype imputation in large pedigrees with faster computation and reduced memory usage.

The paper describes the quality control and integration of genotype calls from two pipelines for whole genome sequencing data in the Alzheimer’s Disease Sequencing Project, resulting in a high-quality consensus dataset.