Cell-Surface LAMP1 is a Senescence Marker in Aging and Idiopathic Pulmonary Fibrosis
Gabriel Meca-Laguna, Michael Qiu, Yafei Hou, Anna Barkovskaya, Apoorva Shankar, Bhavna Dixit, Michael J. Rae, Amutha Boominathan, Amit Sharma
The paper identifies LAMP1 as a cell-surface biomarker for senescent cells in aging and idiopathic pulmonary fibrosis and demonstrates its targeting using a dual antibody-drug conjugate.
Aging Cell · Jun 22, 2025Peer-reviewedMolecular Biology