Complement C3-targeted gene therapy restricts onset and progression of neurodegeneration in chronic mouse glaucoma
Alejandra Bosco, Sarah Anderson, Kevin Breen, Cesar O. Romero, Michael R. Steele, Vince A. Chiodo, Sanford L. Boye, William W. Hauswirth, Stephen Tomlinson, Monica L. Vetter
This study shows that targeting complement C3 with gene therapy reduces neurodegeneration in glaucoma by protecting retinal ganglion cells.
Molecular Therapy · Aug 23, 2018Peer-reviewedNeuroscience