Author

Michael S. Humphrys

University of Maryland, Baltimore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3 Genomics· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Garry S. A. MyersiD· 4 shared Regan J. HaywardiD· 4 shared J. Wallis MarshiD· 3 shared Wilhelmina May HustoniD· 3 shared Amol Carl ShettyiD· 1 shared Anup MahurkariD· 1 shared Bing MaiD· 1 shared Jacques RaveliD· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersSystems Biology

Garry S. A. MyersORCID

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Author profile →

5 papers

Recent·Most cited

Dual RNA-Seq analysis of in vitro infection multiplicity in Chlamydia-infected epithelial cells

Regan J. Hayward, Michael S. Humphrys, Wilhelmina May Huston, Garry S. A. Myers

The paper uses dual RNA-seq to analyze transcriptomic responses in Chlamydia-infected epithelial cells across different infection conditions and RNA depletion methods.

Scientific Reports · May 17, 2021Peer-reviewedSystems Biology

Chromatin accessibility dynamics of Chlamydia-infected epithelial cells

Regan J. Hayward, J. Wallis Marsh, Michael S. Humphrys, Wilhelmina May Huston, Garry S. A. Myers

This study uses FAIRE-Seq to analyze chromatin accessibility changes in human epithelial cells infected with Chlamydia trachomatis over its developmental cycle, identifying differentially accessible regions linked to immune and metabolic responses.

Epigenetics & Chromatin · Oct 27, 2020Peer-reviewedSystems Biology

VIRGO, a comprehensive non-redundant gene catalog, reveals extensive within community intraspecies diversity in the human vagina

Bing Ma, Michael France, Jonathan Crabtree, Johanna B. Holm, Michael S. Humphrys, Rebecca M. Brotman, Jacques Ravel

The paper introduces VIRGO, a gene catalog for the vaginal microbiome, revealing high intraspecies diversity in vaginal communities.

Nature Communications · Feb 26, 2020Peer-reviewedGenomics

Early transcriptional landscapes of Chlamydia trachomatis-infected epithelial cells at single cell resolution

Regan J. Hayward, J. Wallis Marsh, Michael S. Humphrys, Wilhelmina May Huston, Garry S. A. Myers

The paper uses scRNA-Seq to analyze early host cell responses to Chlamydia trachomatis infection, identifying distinct transcriptional patterns and potential biomarkers.

Frontiers in Cellular and Infection Microbiology · Nov 18, 2019Peer-reviewedSystems Biology

Dual RNA sequencing (dRNA-Seq) of bacteria and their host cells

J. Wallis Marsh, Regan J. Hayward, Amol Carl Shetty, Anup Mahurkar, Michael S. Humphrys, Garry S. A. Myers

This paper introduces a method to simultaneously analyze host and bacterial transcriptomes in infected cells and provides a protocol for its implementation.

Briefings in Bioinformatics · Mar 29, 2017Peer-reviewedGenomics