Inhibition of adrenergic b1-AR/Gas signaling promotes cardiomyocyte proliferation through activation of RhoA-YAP axis
Masahide Sakabe, Michael Thompson, Nong Chen, Mark Verba, Aishlin Hassan, Qing Richard Lu, Mei Xin
This study shows that inhibiting β1-AR/Gs signaling promotes cardiomyocyte proliferation and cardiac regeneration in mice by activating the RhoA-YAP axis.
eLife · Dec 8, 2022Peer-reviewedDevelopmental Biology