Author

Mei Xin

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-5732-7501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Dazhuan Eric XiniD· 2 shared Qing Richard LuiD· 2 shared Aishlin HassaniD· 1 shared Arman Esshaghi BayatiD· 1 shared Carl Johannes KoschmanniD· 1 shared Charles B. StevensoniD· 1 shared Emily DengiD· 1 shared Feng ZhangiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Dazhuan Eric XinORCID

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3 papers

Recent·Most cited

A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma

Emily Deng, Xiaowen Zhong, Dazhuan Eric Xin, Upendra Kumar Soni, Wenkun Ma, Xiao Huang, Mingjun Cai, Po-Yu Liang, Jun Bai, Qian Qin, Shreya V. Mishra, Ming Hu, Arman Esshaghi Bayat, Jiajie Diao, Mei Xin, , Q. Richard Lu

This study identifies tonic signaling as a key factor in CAR-T cell efficacy for diffuse midline glioma, showing that restrained tonic signaling improves therapeutic outcomes.

bioRxiv · Sep 29, 2025 · PreprintCancer Biology

Multimodal Validation of the Existence of Transitional Cerebellar Progenitors in the Human Fetal Cerebellum

Zaili Luo, Mingyang Xia, Feng Zhang, Dazhuan Eric Xin, Rohit Rao, Karrie Mei Yee Kiang, Kalen Berry, Yu Xiong, Hongqi Liu, Yifeng Lin, Ming Hu, Mei Xin, Jie Ma, Hao Li, Michael D. Taylor, , Qing Richard Lu

The paper validates the existence of transitional cerebellar progenitors using multimodal approaches across multiple datasets and stages.

bioRxiv · Jun 1, 2025 · PreprintDevelopmental Biology

Inhibition of adrenergic b1-AR/Gas signaling promotes cardiomyocyte proliferation through activation of RhoA-YAP axis

Masahide Sakabe, Michael Thompson, Nong Chen, Mark Verba, Aishlin Hassan, Qing Richard Lu, Mei Xin

This study shows that inhibiting β1-AR/Gs signaling promotes cardiomyocyte proliferation and cardiac regeneration in mice by activating the RhoA-YAP axis.

eLife · Dec 8, 2022Peer-reviewedDevelopmental Biology