Lowering mutant huntingtin by small molecules relieves Huntington's disease symptoms and progression
Anat Bahat, Elad Itzhaki, Benjamin Weiss, Michael Tolmasov, Michael Tsoory, Yael Kuperman, Alexander S. Brandis, Khriesto A. Shurrush, Rivka Dikstein
This study identifies small molecules that lower mutant huntingtin levels, improving HD symptoms and delaying disease progression in mice.
EMBO Molecular Medicine · Feb 19, 2024Peer-reviewedMolecular Biology