Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation
Sung W. Rhee, Irina D. Pokrovskaya, Kelly K. Ball, Michael W. Webb, Jeffrey A. Kamykowski, Oliver Zhao, Elizabeth R. Driehaus, Maria A. Aronova, Sidney W. Whiteheart, Richard D. Leapman, Brian Storrie
The paper maps platelet activation states in thrombi to show how their spatial distribution changes during hemostasis, finding distinct clustering of highly activated platelets at later stages.
bioRxiv · Jul 7, 2024 · PreprintSystems Biology