Irina D. Pokrovskaya

This study maps the molecular organization of Golgi CATCHR complexes and identifies their roles in vesicle tethering and fusion.

This study shows that acute GARP depletion causes vesicle transport defects, leading to mislocalization of Golgi proteins, O-glycosylation issues, and accumulation of vesicle-like structures.

The paper develops a U-Net ensemble method for segmenting cells and organelles in 3D vEM data, achieving state-of-the-art results on CREMI neuron data and murine thrombus platelets.

The paper maps platelet activation states in thrombi to show how their spatial distribution changes during hemostasis, finding distinct clustering of highly activated platelets at later stages.