Author

Michal Brownstien

Hebrew University of Jerusalem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:behavioral assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander BotvinnikiD· 3 shared Bernard LereriD· 3 shared Tzuri Lifschytz· 3 shared Chloe Shevakh· 2 shared Michal Lazar· 2 shared Orr Shahar· 2 shared Amit LotaniD· 1 shared Gilly Wolf· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Alexander BotvinnikORCID

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3 papers

Recent·Most cited

Premorbid Characteristics of the SAPAP3-Mouse Model of Obsessive-Compulsive Disorder: Behavior, Neuroplasticity, and Psilocybin Treatment

Michal Lazar, Michal Brownstien, Alexander Botvinnik, Chloe Shevakh, Orr Shahar, Tzuri Lifschytz, Bernard Lerer

This study examines anxiety-like behaviors and synaptic plasticity in juvenile SAPAP3-KO mice before OCD-like grooming emerges, finding no psilocybin treatment effect and age-dependent synaptic changes.

The International Journal of Neuropsychopharmacology · Mar 29, 2025Peer-reviewedNeuroscience

Striking Long Term Beneficial Effects of Single Dose Psilocybin and Psychedelic Mushroom Extract in the SAPAP3 Rodent Model of OCD-Like Excessive Self-Grooming

Michal Brownstien, Michal Lazar, Alexander Botvinnik, Chloe Shevakh, Karin Blakolmer, Leonard B. Lerer, Tzuri Lifschytz, Bernard Lerer

This study shows that a single dose of psilocybin or psychedelic mushroom extract reduces excessive self-grooming in SAPAP3 KO mice, with effects lasting up to 7 weeks.

Molecular Psychiatry · Oct 11, 2024Peer-reviewedPharmacology & Toxicology

Role of 5-HT2A, 5-HT2C, 5-HT1A and TAAR1 receptors in the head twitch response induced by 5-hydroxytryptophan and psilocybin: Translational implications.

Orr Shahar, Alexander Botvinnik, Noam Esh-Zuntz, Michal Brownstien, Rachel Wolf, Amit Lotan, Gilly Wolf, Bernard Lerer, Tzuri Lifschytz

This study investigates the role of 5-HT2A, 5-HT2C, 5-HT1A, and TAAR1 receptors in modulating head twitch response induced by 5-HTP and psilocybin in mice, showing their potential therapeutic relevance.

International Journal of Molecular Sciences · Nov 16, 2022Peer-reviewedNeuroscience