Sleep deprivation triggers somatostatin neurons in prefrontal cortex to initiate nesting and sleep via the preoptic and lateral hypothalamus
Kyoko Tossell, Xiao Yu, Berta Anuncibay Soto, Mikal Vicente, Giulia Miracca, Panagiotis Giannos, Andawei Miao, Bryan Hsieh, Ying Ma, Raquel Yustos, Alexei L. Vyssotski, Timothy G. Constandinou, Nicholas P. Franks, William Wisden
The paper identifies a circuit pathway in mice where sleep-deprived prefrontal cortex neurons trigger nesting and sleep via connections to the preoptic and hypothalamus.
bioRxiv · Jul 1, 2020 · PreprintNeuroscience