Ying Ma

A REM-active basal ganglia circuit that regulates anxiety

This paper identifies a REM-active basal ganglia circuit in mice that regulates REM sleep and anxiety by showing its role in sleep duration and behavioral responses to aversive stimuli.

Sleep deprivation triggers somatostatin neurons in prefrontal cortex to initiate nesting and sleep via the preoptic and lateral hypothalamus

The paper identifies a circuit pathway in mice where sleep-deprived prefrontal cortex neurons trigger nesting and sleep via connections to the preoptic and hypothalamus.

Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior

This study shows that dysfunction of VTA GABA neurons leads to mania-like behaviors, including increased wakefulness and reduced sleep, which can be reversed by valproate.

Glioma-induced alterations in neuronal activity and neurovascular coupling during disease progression

This study tracks glioma progression in mice, showing decreased neuronal synchrony, disrupted neurovascular coupling, and seizure-related hypoxia in infiltrated cortex.

Galanin neurons in the hypothalamus link sleep homeostasis, body temperature and actions of the alpha2 adrenergic agonist dexmedetomidine

This study shows that galanin neurons in the hypothalamus regulate sleep homeostasis, body temperature, and the effects of dexmedetomidine.

Penalized matrix decomposition for denoising, compression, and improved demixing of functional imaging data

~2-4x SNR gains and 20-300x compression on calcium and voltage imaging, from a patch-wise penalized matrix decomposition that splits signal from temporally uncorrelated noise without hyperparameter tuning.