Biomimetic biaxial mechanical properties enhance hemodynamic performance and prevent adverse tissue remodelling in tissue-engineered heart valves
Bahram Mirani, Sean O. Mathew, Min Namgung, Neda Latifi, Cassandra Chiao-Ying Yao, Brian G. Amsden, Craig A. Simmons
This study shows that tissue-engineered heart valves with native biaxial mechanical properties perform better and avoid fibrosis compared to those with non-physiological mechanics.
bioRxiv · Mar 2, 2025 · PreprintBioengineering