Neda Latifi

This paper describes a method to generate valvular interstitial cells from human pluripotent stem cells, showing high transcriptional similarity to primary fetal VICs and recapitulating disease features in an in vitro model.

This study examines structural and mechanical changes in the main pulmonary artery in pulmonary arterial hypertension and links them to impaired right ventricular function and coupling.

This study shows that tissue-engineered heart valves with native biaxial mechanical properties perform better and avoid fibrosis compared to those with non-physiological mechanics.