Bahram Mirani

Adverse structural and mechanical remodelling of main pulmonary artery in experimental pulmonary arterial hypertension is associated with impaired right ventricle-pulmonary artery coupling and function

This study examines structural and mechanical changes in the main pulmonary artery in pulmonary arterial hypertension and links them to impaired right ventricular function and coupling.

Biomimetic biaxial mechanical properties enhance hemodynamic performance and prevent adverse tissue remodelling in tissue-engineered heart valves

This study shows that tissue-engineered heart valves with native biaxial mechanical properties perform better and avoid fibrosis compared to those with non-physiological mechanics.