Uric acid lowering treatment alleviates perivascular carotid collar placement induced neointimal lesions in Uricase knockout mice
Jie Lu, Ming-Shu Sun, Xin-Jiang Wu, Xuan Yuan, Zhen Liu, Xiao-Jie Qu, Xiao-Peng Ji, Tony R Merriman, Chang-Gui Li
This study shows urate worsens carotid neointimal lesions in hyperuricemic mice, but urate-lowering treatment reduces these effects.
bioRxiv · Jul 10, 2018 · PreprintPhysiology