Author

Jie Lu

Children's Hospital of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Adam C. Richert· 1 shared Ahmet Toksoz· 1 shared Brandon B. Wang· 1 shared Chang-Gui LiiD· 1 shared Colin HenchyiD· 1 shared Edward V. ProchownikiD· 1 shared Eric S. GoetzmaniD· 1 shared Huabo WangiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Adam C. Richert

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2 papers

Recent·Most cited

Reversible Dissociation of Mitochondrial Complex V Balances Anabolic and Energy-Generating Needs in Cancer

Huabo Wang, Jie Lu, Colin Henchy, Steven J. Mullett, Adam C. Richert, Eric S. Goetzman, Ahmet Toksoz, Leonardo Hale, Brandon B. Wang, Nelli Mnatsakanyan, Edward V. Prochownik

The paper shows that dissociation of mitochondrial Complex V into Fo and F1 domains balances anabolic and energy needs in cancer cells by uncoupling ATP synthesis from TCA cycle activity.

iScience · Feb 3, 2026Peer-reviewedCancer Biology

Uric acid lowering treatment alleviates perivascular carotid collar placement induced neointimal lesions in Uricase knockout mice

Jie Lu, Ming-Shu Sun, Xin-Jiang Wu, Xuan Yuan, Zhen Liu, Xiao-Jie Qu, Xiao-Peng Ji, Tony R Merriman, Chang-Gui Li

This study shows urate worsens carotid neointimal lesions in hyperuricemic mice, but urate-lowering treatment reduces these effects.

bioRxiv · Jul 10, 2018 · PreprintPhysiology