Rational reprogramming of cellular states by combinatorial perturbation
Jialei Duan, Boxun Li, Minoti Bhakta, Shiqi Xie, Pei Zhou, Nikhil V. Munshi, Gary C. Hon
The paper develops Reprogram-Seq to screen TF cocktails for reprogramming cell states, identifying a 3-TF combination that reprograms MEFs to epicardial-like cells.
Cell Reports · Jun 1, 2019Peer-reviewedGenomics