Jialei Duan

The paper uses single-cell overexpression screens to study how combinations of transcription factors drive gene regulatory networks and cell-type specific gene expression programs.

This paper develops an optimized protocol for large-scale production of human blastoids and identifies signaling pathways and endometrial stromal effects in blastocyst development.

The paper develops Reprogram-Seq to screen TF cocktails for reprogramming cell states, identifying a 3-TF combination that reprograms MEFs to epicardial-like cells.