Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning
Vanessa E. Gray, Katherine A. Sitko, Floriane Z. Ngako Kameni, Miriam Williamson, Jason J. Stephany, Nicholas Hasle, Douglas M. Fowler
The paper uses deep mutational scanning to analyze Aβ42 aggregation in yeast, identifying key residues and validating structural models.
G3 Genes Genomes Genetics · Sep 26, 2019Peer-reviewedMolecular Biology