Vanessa E. Gray

The paper uses deep mutational scanning to analyze Aβ42 aggregation in yeast, identifying key residues and validating structural models.

This paper introduces VAMP-seq, a method to assess the abundance of protein variants, and identifies pathogenic variants in PTEN and TPMT.

The paper analyzes 34,373 mutations across fourteen proteins to evaluate if alanine substitutions are optimal for identifying functionally important positions, finding that histidine and asparagine are better in many cases.