The Power of Three: Dynactin associates with three dyneins under load for greater force production
Lu Rao, Xinglei Liu, Mirjam Arnold, Richard J. McKenney, Kristy R. Stengel, Simone Sidoli, Florian Berger, Arne Gennerich
The paper shows that mechanical tension recruits a third dynein motor to DDB complexes, enhancing force production and stability under load.
bioRxiv · Jan 14, 2025 · PreprintBiophysics