Highly efficient induction of functionally mature excitatory neurons from feeder-free human ES/iPS cells
Zhi Zhou, Wataru Kakegawa, Koki Fujimori, Misato Sho, Rieko Shimamura, Sopak Supakul, Sho Yoshimatsu, Jun Kohyama, Michisuke Yuzaki, Hideyuki Okano
This study develops a feeder-free method to efficiently generate mature excitatory neurons from human ES/iPS cells, showing high purity and functional characteristics relevant to neurodegenerative disease research.
bioRxiv · Feb 10, 2023 · PreprintNeuroscience