SARS-CoV-2 modulates NK cell responses via induction of HLA-E and triggers expansion of adaptive NK cells during acute infection
Mohammad Zahidul Hasan, Maren Claus, Nadine Krüger, Sarah B. Reusing, Eline Gall, Christina Bade‐Doeding, Armin C. Braun, Carsten Watzl, Markus Uhrberg, Lutz Walter
This study shows SARS-CoV-2 increases HLA-E expression via spike protein processing, modulating NK cell function by affecting canonical and adaptive NK cells differently during acute infection.
Emerging Microbes & Infections · May 28, 2024Peer-reviewedImmunology