Penalized matrix decomposition for denoising, compression, and improved demixing of functional imaging data
E. Kelly Buchanan, Ian Kinsella, Ding Xuan Zhou, Rong Zhu, Pengcheng Zhou, Felipe Gerhard, John Ferrante, Ying Ma, Sharon H. Kim, Mohammed Shaik, Yajie Liang, Rongwen Lu, Jacob Reimer, Paul G. Fahey, Taliah Muhammad, , Liam Paninski
~2-4x SNR gains and 20-300x compression on calcium and voltage imaging, from a patch-wise penalized matrix decomposition that splits signal from temporally uncorrelated noise without hyperparameter tuning.
bioRxiv · Jan 21, 2019 · PreprintNeuroscience