Cancer BiologybioRxivPreprint
SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis
Ricardo Coelho, Brinton A. Seashore-Ludlow, Sarah Schütz…·Francis Jacob
This study shows SMAC mimetics overcome apoptotic resistance in ovarian cancer by targeting the MSLN-TNF alpha axis, enhancing cell death and synergizing with chemotherapy.