Repurposing the biased visibility in HiC datasets to mark dynamically regulated condensed and decondensed chromatin states genome-wide.
Keerthivasan Raanin Chandradoss, Prashanth Kumar Guthikonda, Srinivas Kethavath, Monika Dass, Harpreet Singh, Rakhee Nayak, Sreenivasulu Kurukuti, Kuljeet Singh Sandhu
The paper shows HiC datasets have bias due to chromatin condensation, which can be used to study dynamic chromatin states.
bioRxiv · Mar 31, 2019 · PreprintGenomics