Transcriptional and Cellular Response of hiPSC-derived Microglia-Neural Progenitor Co-Cultures Exposed to IL-6
Amalie C. M. Couch, Amelia M. Brown, Catarina Raimundo, Shiden Solomon, Morgan Taylor, Laura Sichlinger, Rugilė Matulevičiūtė, Deepak P. Srivastava, Anthony Christopher Vernon
The paper investigates how IL-6 exposure affects hiPSC-derived microglia-neural progenitor co-cultures, finding minimal transcriptional response in NPCs despite MGLs secreting IL-6R.
Brain Behavior and Immunity · Aug 2, 2024Peer-reviewedNeuroscience