Central amygdalar PKCδ neurons mediate fentanyl withdrawal
Lisa M. Wooldridge, Jacqueline W. K. Wu, Adrienne Y. Jo, Morgan Zinn, Angela M. Lee, Malaika Mahmood, Savanna A. Cohen, Nora M. McCall, Corinna S. Oswell, Sophie A. Rogers, Gregory F. Corder
This study identifies PKCδ neurons in the central amygdala as key mediators of fentanyl withdrawal by showing their hyperactivity and role in withdrawal signs.
Neuropsychopharmacology · Dec 19, 2025Peer-reviewedNeuroscience