Lisa M. Wooldridge

The paper identifies a cortical circuit in mice modulated by opioids and develops a gene therapy to mimic opioid analgesia for chronic pain.

This study identifies PKCδ neurons in the central amygdala as key mediators of fentanyl withdrawal by showing their hyperactivity and role in withdrawal signs.

This paper creates an anatomical and molecular atlas of the nociceptive medial thalamus, identifying a distinct population of opioid receptor-expressing neurons involved in pain processing.

The paper develops a behavioral analysis pipeline using LUPE to quantify opioid withdrawal behaviors in mice, identifying challenges in capturing rapid behaviors and laying groundwork for standardized quantification.

This study identifies a BLAnoci ensemble in the basolateral amygdala that mediates both acute and chronic pain behavior through a novel amygdala-striatal circuit involving the nucleus accumbens shell.