Crosstalk between the Ino80 complex and TOR signaling drives fungal adaptation to hypoxia through chromatin remodeling
Manjari Shrivastava, Faïza Tebbji, Morgane Dubé, Antony T. Vincent, Adnane Sellam
This study identifies the TOR signaling pathway and Ino80 chromatin-remodeling complex as key regulators of hypoxic adaptation in Candida albicans by coordinating phosphate homeostasis and chromatin accessibility.
bioRxiv · Dec 19, 2025 · PreprintMicrobiology