Faïza Tebbji

A new fungal taurine biosynthetic pathway promotes metabolic fitness and virulence in Candida albicans

This study identifies a novel fungal taurine biosynthetic pathway in Candida albicans, showing its role in metabolic fitness and virulence.

Isw2-mediated chromatin remodeling governs antifungal tolerance and heteroresistance in Candida albicans

This study identifies Isw2-mediated chromatin remodeling as a regulator of antifungal tolerance and heteroresistance in Candida albicans, revealing its role in suppressing CRZ1 transcription and modulating drug responses.

Met32 governs transcriptional control of sulfur metabolic flexibility and resistance to reactive sulfur species in the human fungal pathogen Candida albicans

This study identifies Met32 as a master regulator of sulfur utilization and resistance to reactive sulfur species in C. albicans, highlighting its role in fungal virulence.

Crosstalk between the Ino80 complex and TOR signaling drives fungal adaptation to hypoxia through chromatin remodeling

This study identifies the TOR signaling pathway and Ino80 chromatin-remodeling complex as key regulators of hypoxic adaptation in Candida albicans by coordinating phosphate homeostasis and chromatin accessibility.

High resolution genome-wide occupancy in Candida spp. using ChEC-seq

The paper introduces ChEC-seq, a PCR-based method for high-resolution genome-wide occupancy mapping of transcriptional regulators in Candida species, demonstrating its application on the SWI/SNF complex and NsiI.