Antidepressant-like effects of P2 purinergic antagonist PPADS is dependent on serotonergic and noradrenergic integrity
Cassiano R. A. F. Diniz, Murilo Rodrigues, Plínio C. Casarotto, Vítor S. Pereira, Carlos C. Crestani, Sâmia R. L. Joca
This study shows that the antidepressant-like effect of PPADS depends on serotonergic and noradrenergic systems, as its effect is blocked by depleting these systems.
bioRxiv · Nov 10, 2016 · PreprintPharmacology & Toxicology