Sâmia R.L. Joca

This study shows prenatal THC exposure reduces metabolic gene expression and KEAP1 in mouse placental labyrinth, while CBD has no significant effect.

This study shows that high-intensity fear engrams causally contribute to cognitive and affective dysfunction beyond threat processing in mice.

This study shows antidepressants interact with estrogen receptor alpha and its signaling pathways, suggesting a new mechanism for their therapeutic effects in mood disorders.

This study shows that chronic morphine exposure alters the transcriptomic and proteomic content of brain-derived extracellular vesicles from the prefrontal cortex, which can reprogram recipient neurons.

This study characterizes FSL, FRL, and SD rats in fear-memory paradigms to identify resilience and susceptibility to PTSD and co-morbid depression, finding differences in conditioned responses and endocrine stress responses.

This study shows that fluoxetine modulates fear memory extinction via Trk-dependent mechanisms in both dorsal and ventral hippocampus, with distinct effects in each subregion.

The paper shows that repeated aminoguanidine administration increases TRKB phosphorylation in the dPAG, which is necessary for its panicolytic-like effect in rats.

This study evaluates the impact of different anesthetics on rat behavior in antidepressant and anxiolytic-like tests, finding that some anesthetics affect anxiety-related behaviors but not antidepressant responses.

This study shows anandamide activates TRKB through CB1 and TRPV1 receptors, influencing neuronal migration and behavior in rat cortical cells.

The paper examines transcript levels of P2x7r and P2x4r in FSL and FRL rats, finding elevated transcripts in FSL rats in specific brain regions.

This study shows that isoflurane anesthesia produces antidepressant-like effects in rodents by activating TrkB signaling and related molecular pathways.

This study shows that the antidepressant-like effect of PPADS depends on serotonergic and noradrenergic systems, as its effect is blocked by depleting these systems.