Insertion of rare autism variants in synaptic genes induce novel behavioral phenotypes in C. elegans
Dustin Haskell, William R. Haury, Myra Granato, Brandon L. Bastien, Michael P. Hart
The paper inserts rare autism variants in C. elegans synaptic genes and assesses their functional impact on behavior, revealing complex effects including loss and gain of function.
bioRxiv · Dec 22, 2025 · PreprintGenetics