N. A. Lesniak

This study shows that a simplified fecal community transplant can restore colonization resistance to antibiotic-perturbed murine gut communities, preventing Clostridioides difficile colonization depending on the community structure.

This study shows that gut bacterial communities influence the severity of Clostridioides difficile infections in mice, with certain bacterial groups linked to more or less severe outcomes.

This study shows that PEG laxative treatment in mice increases susceptibility to C. difficile colonization and delays clearance.

The paper develops a two-day workshop curriculum for teaching reproducible research using R, Unix, git, and GitHub, addressing content overload and integration challenges in existing curricula.

The paper investigates how different antibiotic treatments affect the gut microbiota's ability to clear C. difficile colonization, finding antibiotic-specific community changes associated with clearance.

This paper evaluates ML models for predicting colonic neoplasias using 16S rRNA data, finding that L2-regularized logistic regression offers a balance of performance, speed, and interpretability.

This study shows omeprazole does not promote C. difficile colonization in mice, even when combined with clindamycin, suggesting it does not disrupt microbiota resistance to CDI.

This study finds that fecal SCFA concentrations are not associated with colonic tumor status and cannot be predicted from bacterial community structure.