Author

N. Bai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Karanicolas· 2 shared A. K. Gupta· 1 shared D. K. Johnson· 1 shared E. A. Golemis· 1 shared I. Bychkov· 1 shared L. Lan· 1 shared L. Xu· 1 shared M. M. Pillai· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

J. Karanicolas

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Author profile →

2 papers

Recent·Most cited

Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry

N. Bai, Y. Adeshina, I. Bychkov, Y. Xia, R. Gowthaman, S. A. Miller, A. K. Gupta, D. K. Johnson, L. Lan, E. A. Golemis, P. B. Makhov, L. Xu, M. M. Pillai, Y. Boumber, J. Karanicolas

This paper designs inhibitors for Musashi proteins MSI1 and MSI2 by mimicking hotspot pharmacophores from protein-RNA complexes, showing specificity and activity in multiple assays.

bioRxiv · Jan 9, 2023 · PreprintBiochemistry

Rationalizing PROTAC-mediated ternary complex formation using Rosetta

N. Bai, P. Kirubakaran, J. Karanicolas

This paper introduces a computational method using Rosetta to model PROTAC ternary complex formation, showing it can explain PROTAC activity and selectivity without requiring extensive experimental testing.

bioRxiv · May 27, 2020Biochemistry