Author

N. D. Rochman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

E. V. Koonin· 5 shared Y. I. Wolf· 5 shared F. Zhang· 3 shared G. Faure· 3 shared P. Mutz· 2 shared A. Holland· 1 shared A. P. Bosse· 1 shared B. Lambrus· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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5 shared papersEvolutionary Biology

E. V. Koonin

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Author profile →

6 papers

Recent·Most cited

Unicellular life balances asymmetric allocation and repair of somatic damage representing the origin of r/K selection

D. Biba, Y. I. Wolf, E. V. Koonin, N. D. Rochman

This study uses mathematical modeling to show that optimal strategies for balancing somatic damage repair and asymmetric allocation depend on extrinsic mortality and damage accumulation rates, linking these to the evolutionary r/K selection theory.

bioRxiv · Nov 21, 2023 · PreprintEvolutionary Biology

Host Age Structure Defines Interactions with Pathogens: Grandparent Effect under Collaboration and Virulent Mutualism under Competition

C. O. S. Portner, E. G. Rong, J. A. Ramirez, Y. I. Wolf, A. P. Bosse, E. V. Koonin, N. D. Rochman

The paper uses mathematical modeling to show how host age structure affects pathogen interactions, finding that virulent pathogens can benefit competitive populations while harming collaborative ones.

bioRxiv · Aug 16, 2022 · PreprintEvolutionary Biology

Human pathogenic RNA viruses establish non-competing lineages by occupying independent niches

P. Mutz, N. D. Rochman, Y. I. Wolf, G. Faure, F. Zhang, E. V. Koonin

This study analyzes 27 human pathogenic RNA viruses to show they form multiple co-circulating lineages with low turnover rates, occupying non-competing epidemiological niches.

bioRxiv · Dec 10, 2021 · PreprintEvolutionary Biology

Epistasis at the SARS-CoV-2 RBD Interface and the Propitiously Boring Implications for Vaccine Escape

N. D. Rochman, G. Faure, Y. I. Wolf, P. Freddolino, F. Zhang, E. V. Koonin

This study analyzes epistatic interactions among RBD mutations in SARS-CoV-2 variants to assess their impact on vaccine escape potential.

bioRxiv · Aug 30, 2021 · PreprintMicrobiology

Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2

N. D. Rochman, Y. I. Wolf, G. Faure, P. Mutz, F. Zhang, E. V. Koonin

This study analyzes 300,000 SARS-CoV-2 genomes to show ongoing adaptive evolution, with positive selection in spike and nucleocapsid proteins and regional diversification over time.

bioRxiv · Oct 12, 2020Microbiology

YAP/TAZ as a Novel Regulator of cell volume

N. A. Perez Gonzalez, N. D. Rochman, K. Yao, J. Tao, M.-T. Tran Le, S. Flanary, L. Sablich, B. Toler, E. Crentsil, F. Takaesu, B. Lambrus, J. Huang, V. Fu, A. Holland, S. An, , S. Sun

This study identifies YAP/TAZ as regulators of single-cell volume, showing their role extends beyond cell cycle duration and shape, and they influence division volume independently of mTOR.

bioRxiv · Jan 23, 2019Bioengineering